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The Nobel Prize—The first 100 years

by Renan Uflacker, M.D.  
Radiology
The year 2001 marks the 100th anniversary of the Nobel prizes. 

More than 700 laureates have received this prize for their outstanding contributions to human kind. The prize goes to persons recognized for achievements in physics, chemistry, medicine, literature, peace and economics.
 
The Nobel Prize is the most coveted intellectual prize of all, and perhaps the most controversial, as well. To the intellectual world, a Nobel Prize is as desirable as an Oscar to an actor or Olympic gold to an athlete. However, the dignity, etiquette and formality that are the hallmark of Nobel prize-giving are a world away from the self-congratulatory exercise of the Oscars. Yet the prizes are undisputed arbiters of greatness. They have come to represent a universal view of the world, not a Scandinavian one.
 
It might be difficult for us, as common people, to understand what an individual laureate has done that is so admirable, particularly in some cryptic areas of sciences. But it is easier to understand the Nobel stamp of approval. The Nobel brand name has survived for 100 years and thrived, rather than lose its impact in the midst of the controversies that frequently surrounded it.
 
The prize's prestige has a lot to do with Alfred Nobel himself. Best known as the inventor of dynamite, he was a very creative man, with dozens of patented inventions to his credit. He also was an entrepreneur who built a 19th century business empire throughout Europe and the United States that was a precursor of the multinational enterprises of today. 
 
Born in Sweden, Alfred Nobel grew up in Saint Petersburg, Russia, where his father worked for the Russian Imperial Army as an engineer specializing in explosives. Alfred Nobel became very wealthy, producing and selling dynamite, in a time of construction boom at the end of the 19th century. Roads, railroads built throughout the world and the Panama canal were some of the projects that depended on his dynamite supplies. Nobel traveled worldwide, on ship, train, horse and carriage to oversee and manage the company and the ongoing projects. With time he established five residencies in different parts of the world, all with a private laboratory for the pursuit of his personal projects. 
 
Despite being a “globalist” long before the term was invented, Nobel was a lonely, melancholic man with a passion for poems of Shelley, and, in his own words, “digested philosophy more efficiently than food.” He was constantly haunted by the premature death of his brother, and business partner, in an accident with explosives, which led him to invent the dynamite, solving the problem of the instability of nitroglycerin. He never settled in one country and never married. Although he did have several female partners throughout his life he did not have any children. 
 
By the time he died in 1896, in Italy,  Nobel had built a considerable fortune. His will dictated that a fund should be constituted by his will executors and the whole capital of his realizable estate should be invested in safe securities, and the interest on which should be distributed in the form of prizes to those who, during the preceding year, conferred the greatest benefit on mankind. 
 
Nobel changed his will countless times but the final version can be excerpted as follows: “The interest of the investment shall be divided in five equal parts. One part to the person who shall have made the most important discovery or invention in the field of physics; one part to the person who shall have  made the most important chemical discovery or improvement; one part to the person who shall have made the most important discovery within the domain of physiology or medicine; one part to the person who shall have produced in the field of literature the most outstanding work of an idealistic tendency; and one part to the person who shall have done the most or the best work for fraternity between nations, for the abolition or reduction of standing armies and for the holding and promotion of peace congresses. 
 
The prizes for physics and chemistry shall be awarded by the Swedish Academy of sciences; that for physiology or medical works by the Karolinska Institute in Stockholm; that for literature by the Academy in Stockholm and for champions of peace by a committee of five persons to be elected by the Norwegian Storting”  (Norwegian Parliament). 
 
In congruence with his globalist view of the world, and in defiance of the nationalistic spirit of the times he further stated: “In awarding of the prizes no consideration be given to the nationality of the candidates, but that the most worthy shall receive the prize, whether he be Scandinavian or not.” 
 
The Nobel Foundation was incorporated to administer the prizes and run the finances, and the first Nobel Prizes were awarded in 1901. A sixth prize, for economics, was added in 1969 to celebrate the 300th anniversary of the Swedish central bank The first individual prize in 1901 was SKr150,000, this year each prize is worth SKr10,000,000, or about US$1,000,000.
 
Controversy started on day one of the Nobel Prize history. The Scandinavians were outraged that others than Scandinavians would be considered to receive the award. When the first literature prize went to a little-known French author, Sully Prudhomme, in 1901,  rather than Tolstoy, already one of the most prominent authors in the world, there was uproar on the streets of Europe. 
 
The most likely prizes to provoke controversy are the ones in the fields of literature and peace. Henry Kissinger was awarded one for peace, but Gandhi wasn't. Churchill, in 1953, got one for literature but Tolstoy didn't. Few peace awards have been more controversial than that awarded to Henry Kissinger in 1973, a brilliant man but associated more with the fighting in Vietnam than any peace that followed. More recently, in 1994, Yassir Arafat, Simon Peres and Yitzhak Rabin shared the Peace Prize, awarded by the Norwegian Peace Prize committee in recognition of the importance of the Oslo accord as a milestone for peace in the Middle East. We now know how important that milestone was, or wasn’t. 
 
The award of the Nobel to Martin Luther King Jr., in 1964, however, is an unanimity. This year the Norwegian Nobel Committee will have to think long and careful about the peace prize. Following the unfortunate events here in US the committee should feel inappropriate to award a peace prize for 2001.
 
While winning a Nobel prize has catapulted into the spotlight some people that would be otherwise in perennial obscurity, there is no guarantee of lasting celebrity. Nowadays, being recommended in Oprah's book club generates more sales of books worldwide than winning the Nobel Prize of literature. 
 Some argue that winning the prize is the kiss of death for future creativity; others that the prizes only go to people already past their prime, already in retirement or close to death due to old age. 
 
However, in regards to science, the appreciation for a breakthrough achievement and the realization of the importance of a discovery may take several years. The development of the research in some areas take time and the original author of the idea or discovery may not be the one that finds the application or put together the final facts and confirmation for the achievement. 
 
In literature there is no less controversy than in other areas. Any list of the 10 most famous writers who did not get the Nobel would match a list of the 10 most famous who did. In literature, it seems that the recognition of the body of work of the author is more important than the individual work or exceptional book published in the preceding years. The tendency is to award mature authors, instead of younger generation, creative writers. 
 
Some say that the Swedish Academy should create an equivalent to the “Salon de Refuses” (in analogy to the, now overwhelmingly famous,  impressionist painters to whom were refused access to the official exhibition of the French Academy of Arts in 1863, and promoted a separate exhibition), listing the many great writers of the 20th century who did not win the prize and giving the reasons.  
 
Even in their own back yard, the Nobel committee ignored Ibsen. But Ibsen was Norwegian, not Swedish. The French writer Jean-Paul Sartre, is one of only two people to refuse a Nobel Prize. He held that such honor could interfere with a writer’s responsibilities to his readers (the other was Le Duc Tho, co-winner with Kissinger of the peace prize in 1973).
 
Only a handful of females have won the prize(15), although the exceptional Marie Curie received the Nobel Prize in physics in 1903 and chemistry in 1911, joining a very exclusive club, of two time winners, with Linus Pauling (1954 chemistry and 1962 peace). 
 
This happened at a time when women were not supposed to get an education, much less be a scientist. Other women also won the prize, in literature, peace and sciences (including Irene Joliot-Curie, chemistry in 1935, Marie Curie’s daughter) and it seems that to the Nobel Committee there is an increased awareness of the role of women in sciences, literature and world events, as demonstrated by the current Nobel Foundation’s Centennial Exhibition in Stockholm.
 
The competence of the judges has also been forever questioned because it consists of Swedes and Norwegians only, theoretically lacking the universality necessary to judge the heights of human intellectual and scientific achievements. Every time the annual list of prize recipients is published, dozens of writers, scientists and pacifists throughout the world are pointed out by the media and critics as deserving the recognition of the Nobel Prize, but had been forgotten. 
 
In physiology and medicine there are many examples of overlooked scientists, even from Sweden. Sven Seldinger from the Karolinska Institute, home of the Nobel committee for physiology and medicine, developed in 1953, what is called now the “percutaneous technique,” consisting of the needle replacement with a guidewire, for catheter insertion in the vascular system. This simple contribution allowed a complete revolution in medicine with the performance, throughout the world, of literally millions of lifesaving catheterization procedures every year, for the past 50 years. 
 
Seldinger was never considered for the Nobel prize and died anonymously in 1998. On the other hand the Nobel Committee was too fast in awarding the Nobel of medicine in 1949 to the Portuguese scientist Dos Santos for the development of the now infamous frontal cerebral lobotomy, using a needle inserted through the eye socket. Paradoxically, the same scientist had developed the technique of cerebral angiography with the intravascular injection of iodinated contrast material, in 1920, which was the major breakthrough for the study of the brain for most of the 20th century, and went unrecognized by the Nobel committee. 
 
Even Albert Einstein was a victim of this oversight. He received the Nobel prize in physics for an important but minor contribution, related to the explanation of the so called Brownian movement of the molecules, which palled in comparison with his major achievement related to the development of  the theory of the relativity. Maybe the committee settled for the less controversial achievement.
 
For all the controversy, however, the reputation of the Nobel is secure. The prizes would not have retained their prestige if the judges had not made the right decisions often enough. The system, however, may have to change, to allow more than three winners to share each prize. Currently, only the peace prize can be won by an organization or institution. In sciences, it is necessary to allow a team, a group, or a department to win. The way science is nowadays, there is almost no single scientist that is truly responsible for one achievement. Science is a team effort.
 
Courage to think in entirely new directions, daring to question established theories, innovative combinations of insights from different fields— these are some of the characteristics of creative ability that are considered for the Nobel award, and that, has been the reality of the Nobel Prize for the last 100 years. The commemorations of the anniversary of the Noble Prize include a Centennial Exhibition at the Nobel Museum in Gamla Stan, in the heart of Stockholm. The main theme of the exhibition is creativity: “What is creativity and how can creativity best be encouraged?” “Which is more important to the creative process: the individual or the environment?” The centennial exhibition illustrates these questions by presenting the laureates and respective milieus from the 100-year history of the Nobel Prize. 
 
The exhibition, however, does not provide any answers, but gives the visitor the chance to ponder over these questions. 
 
Visiting this museum we think. We think about access to education, quality of education, freedom of choice, professional choice, academic freedom, needs of support to create the milieu, development of scientific endeavors, inspiration, hard work, challenge, curiosity. 
 
We think creativity.